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Hjärnfondens (The Swedish Brain Foundation’s) Alzheimer Symposium
April 9 @ 08:15 - 17:00
Welcome to a symposium about decoding molecular pathways and biomarkers for future therapies for Alzheimer’s disease!
The symposium will feature expert-led sessions, keynote lecture and in-depth discussions on novel biomarkers, neuroimaging, and drug development. Network with leading scientists and explore the latest breakthroughs in Alzheimer research.
Program
| 8:15–9:00 |
Registration |
| 9:15–9:20 |
Introduction and welcome to the symposiumProfessor Cecilia Lundberg, |
| 9:20–10:05 |
Keynote lecture: Alzheimer’s disease: From molecular pathways to clinical hallmarksProfessor Bart De Strooper, |
| 10:05–11:50 |
SESSION I: The role of brain vasculature and amyloid fibril polymorphism in Alzheimer’s disease progressionChairs: Christer Betsholtz (KI) and Per Hammarström (LiU) 10:05–10:25 What role does the blood-brain barrier play in Alzheimer’s disease?Professor Christer Betsholtz, |
| 10:25–10:50 |
Coffee and mingle10:50–11:30 The potential for amyloid-beta transmission: What the evidence tells usAssociate Professor and Honorary Consultant Neuropathologist, Zane Jaunmuktane, 11:30–11:50 The role of fibril polymorphism of experimentally transmissible Aβ-amyloid seedsProfessor Per Hammarström, |
| 11:50–13:00 |
Lunch |
| 13:00–14:20 |
SESSION II: Novel Alzheimer’s biomarkers and mechanistic insights into disease progressionChairs: Kaj Blennow (GU) and Martin Hallbeck (LiU) 13:00–13:20 Aβ and tau AD biomarkers in CSF and blood – What do and don’t tell us about brain pathophysiologyProfessor Kaj Blennow, 13:20–13:40 Tau is tethered within EVs: Insights into the genesis of secreted tau species in human brainPhD Steph Fowler, 13:40–14:00 The role of autophagy in Alzheimer’s disease – Potential for treatmentAssociate Professor Per Nilsson, 14:00–14:20 From endosomes to vesicles: Cellular pathways driving Alzheimer’s diseaseProfessor Martin Hallbeck, |
| 14:20–15:00 |
Coffee and mingle |
| 15:00–16:20 |
SESSION III: Neuroimaging and drug development: Advancing novel treatment approaches for Alzheimer’s diseaseChairs: Stina Syvänen (UU) and Janne Johansson (KI) 15:00–15:40 TBDProfessor Tuomas Knowles, 15:40–16:00 Prevention of amyloid-associated neurotoxicity by the BRICHOS domain – Molecular mechanisms and therapeutic potentialProfessor Janne Johansson, 16:00–16:20 Bispecific antibody formats for neuroimaging and therapeuticsProfessor Stina Syvänen, |
| 16:20–16:40 |
Panel discussionModerator: Professor Cecilia Lundberg, |
| 16:40–16:45 |
Concluding remarks |